吴磊教授科研团队

发布日期: 2016-11-09浏览次数:

科研团队(课题组):天然产物化学

课题组负责人:吴磊,025-84395351Email: rickywu@njau.edu.cn 

1.主要研究方向:

1) 功能性含膦有机化合物高效构筑方法;

2) 有机配体稳定的纳米金属及金属有机骨架(MOF)催化材料;

3) 具生物活性天然产物(药物)全合成。

2. 团队成员: 吴磊 教授,祝洁 讲师,沙强 讲师

3. 课题组负责人简介:吴磊,1980年生,威廉希尔亚洲公司教授、博士生导师,威廉希尔副经理。2007年博士毕业于中国科学院化学研究所,师从范青华研究员。曾在美国Syracuse University University of Notre Dame从事三年博士后研究。主要研究方向为含膦有机物的合成方法学和金属纳米催化材料,先后主持国家自然科学基金(面上及青年项目)、江苏省自然科学基金(面上项目)、教育部留学回国人员科研启动项目、北京分子科学国家实验室开放基金、威廉希尔亚洲公司高层次引进人才启动基金、哈尔滨工业大学引进人才启动基金等多项科研项目,已在Organic Letters; Journal of Organic Chemistry; Journal of the American Chemical Society; Advanced Synthesis & CatalysisChemistry-A European Journal; Catalysis Science & Technology等国际权威期刊发表论文近三十篇SCI收录论文,其中第1作者及通讯作者论文20篇,累计影响因子>80,他引近300次。2012年为Bentham出版集团Current Organic Chemistry期刊客座编辑。受邀出版英文图书章节两章(德国Wiley和美国Nova Science出版社)。先后入选江苏省教育厅青蓝工程、江苏省科技厅第四期 “333高层次人才培养工程(第三层次)以及南京市“321计划”。为《有机化学》、《化学进展》、《化学学报》、Organic Letters, Advanced Synthesis & Catalysis, Tetrahedron Letters, Journal of Organic Chemistry, RSC Advances, Chemistry-A European Journal, Current Organic Chemistry等国内外知名SCI期刊审稿人。

主要成员:祝洁,1988年生,讲师,博士。2010年在南京理工大学化学工程与工艺专业完成本科学业,获得学士学位,并于同年以硕博连读攻读博士学位,导师陆明教授。2013~2014期间前往日本国立材料研究所做联合培养,导师解荣军教授。2015年获得南京理工大学化学工程与技术专业博士学位,进入willhill官方网站化学系工作。

主要成员:沙强,1989年生,讲师,博士。2010年在南京理工大学制药工程专业获得学士学位后,继续攻读博士学位,导师魏运洋教授。2014.92015.1年在美国马里兰大学帕克分校、2015.12015.9在德克萨斯大学圣安东尼奥分校做联合培养,师从Michael P. Doyle教授。2016年获得南京理工大学化学工程与技术专业博士学位,进入willhill官方网站化学系工作。

4. 课题组主持的国家级科研项目

1. 国家自然科学基金-面上项目;新型手性金属纳米粒子制备及不对称催化性能研究,主持人吴磊,2014-2017;

2. 国家自然科学基金-青年基金;过渡金属催化的新型分子内环化及串联反应研究,主持人吴磊,2011-2013;

3. 国家青年自然科学-青年基金;手性MOFs催化外消旋仲醇的氧化动力学拆分,主持人祝洁,2017-2019

5. 近五年来发表的主要论文

1. Yun-Tao Xia, Xiao-Tao Sun, Ling Zhang, Kai Luo, Lei Wu*, Metal-free Hydrogen Atom Transfer from Water: Expeditious Hydrogenation of N-Heterocycles Mediated by Diboronic Acid, Chemistry-A European Journal, 2016, DOI: 10.1002/chem. 201604503. (SCI IF: 5.771)

2. Wen-Chao Yang, Peng Dai, Kai Luo, Lei Wu*, Iodide/tert-Butyl Hydroperoxide -Mediated Benzylic C–H Sulfonylation and Peroxidation of Phenol Derivatives, Advanced Synthesis & Catalysis, 2016, 358, 3184-3190. (SCI IF: 6.453).

3. Yu Zhang, Jie Zhu, Yun-Tao Xia, Xiao-Tao Sun, Lei Wu*, Efficient Hydrogenation of N-heterocycles Catalyzed by Carbon-Metal Covalent Bonds Stabilized Palladium Nanoparticles: Synergistic Effects of Particle Size and Water, Advanced Synthesis & Catalysis, 2016, 358, 3039-3045. (SCI IF: 6.453).

4. Kai Luo, Yao-Zhong Chen, Li-Xian Chen, Lei Wu*, Autoxidative C(sp2)−P Formation: Direct Phosphorylation of Heteroarenes under Oxygen, Metal-Free, and Solvent-Free Conditions. Journal of Organic Chemistry, 2016, 81, 4682-4689. (SCI IF: 4.785).

5. Kai Luo, Yao-Zhong Chen, Wen-Chao Yang, Jie Zhu, Lei Wu*, Cross-Coupling Hydrogen Evolution by Visible Light Photocatalysis Toward C(sp2)-P Formation: Metal-free C-H Functionalization of Thiazole Derivatives with Diarylphosphine Oxides, Organic Letters, 2016, 18, 452-455. (SCI IF: 6.732, Highlighted by ChemInform, 2016, 47(26)).

6. Yu Zhang, Mao Mao, Yi-Gang Ji, Jie Zhu, Lei Wu*, Modular metal–carbon stabilized palladium nanoparticles for the catalytic hydrogenation of N-heterocycles, Tetrahedron Letters, 2016, 57, 329-332. (SCI IF: 2.347).

7. Yao-Zhong Chen, Ling Zhang, Ai-Min Lu, Fang Yang and Lei Wu*, α‑Allenyl Ethers as Starting Materials for Palladium Catalyzed Suzuki−Miyaura Couplings of Allenylphosphine Oxides with Arylboronic Acids, Journal of Organic Chemistry, 2015, 80, 673-680. (SCI IF: 4.785).

8. Teng Liu, Yun-Tao Xia, Jie Zhu, Ai-Min Lu, Lei Wu*, Metal-free synthesis of chlorinated and brominated phosphinoyl 1,3-butadiene derivatives and its synthetic applications, Tetrahedron Letters, 2015, 56, 6508-6512. (SCI IF: 2.347).

9. Teng Liu, Jie Dong, Shu-Jun Cao, Li-Cheng Guo, Lei Wu*, Suzuki–Miyaura coupling of phosphinoyl-α-allenic alcohols with arylboronic acids catalyzed by a palladium complex “on water”: an efficient method to generate phosphinoyl 1,3-butadienes and derivatives, RSC Advances, 2014, 4, 61722-61726.(SCI IF: 3.708).

10. 季益刚,吴磊*,范青华*,金属/金属氧化物纳米粒子在不对称氢化和氢转移反应中的应用研究进展,化学学报2014, 72, 798-808 (综述约稿, SCI IF: 0.874).

11. Lei Wu*, Immobilized Catalysts for Organic Synthesis: Homogeneous & Heterogeneous, Current Organic Chemistry, 2013, 17, 1235-1235 (Editorial Material).

12. Lei Wu*, Yu Zhang and Yi-Gang Ji, Homogeneous Recyclable Catalysts Based on Metal Nanoparticles for Organic Synthesis (Invited Review). Current Organic Chemistry, 2013, 17, 1288-1302. (SCI IF: 3.064).

13. Yan-fei Wang*, Zhanmin Xiao, Lei Wu*, Metal-nanoparticles Supported on Solid as Heterogeneous Catalysts, Current Organic Chemistry, 2013, 17, 1325-1333. (SCI IF: 3.064).

14. Lei Wu*, Xiao Zhang, Qing-Qing Chen, An-Kun Zhou, A novel copper-catalyzed reductive coupling of N-tosylhydrazones with H-phosphorus oxides, Organic & Biomolecular Chemistry, 2012, 10, 7859-7862. (SCI IF: 3.696).

15. Lei Wu*, Xiăo Zhang and Zhimin Tao, A Mild and Recyclable Nano-sized Catalyst for the Stille Reaction in Water, Catalysis Science & Technology, 2012, 2, 707-710. (SCI IF: 3.575).

16. Lei Wu*, Jie Ling, Zong-quan Wu, a Highly Active and Recyclable Catalyst: Phosphine Dendrimer-Stabilized Nickel Nanoparticles for the Suzuki Coupling Reaction. Advanced Synthesis & Catalysis, 2011, 353, 1452-1456. (SCI IF: 6.048).

17. Lei Wu, Yan-Mei He, Qing-Hua Fan*, Controlled Reversible Anchoring of η6-Arene/TsDPEN-Ru(II) Complex onto Magnetic Nanoparticles: A New Strategy for Catalyst Separation and Recycling. Advanced Synthesis & Catalysis, 2011, 353, 2915-2919. (SCI IF: 6.048).